Endocrine Abstracts

Introduction: The cause of primary hyperparathyroidism (PHPT) is a single adenoma in 85% of cases. Scintigraphy with technetium-sestamibi (MIBI) is the test of choice for localising adenomas in patients with PHPT, allowing minimally invasive surgery in most patients. Some articles recommend thyroid function supression to improve scintigraphy results.Methods: A prospective study was conducted in which 8 patients were included with diagnosis of PHPT and ne...

Objective: To assess improvement in glycemic control in those diabetic patients who have received structured education in diabetes in our Day Hospital.Methods: A retrospective observational study was carried out in which 42 diabetic patients who had attended to educational courses in 1 year were included, determining the age of the patient, type of Diabetes, score obtained in the questionnaires at the beginning and end of the course, as well as HbA1c bef...

Objectives: Our aim is to assess the cardiovascular risk factors that are already present at the time of diagnosing new-onset type 2 diabetes mellitus (DM).Materials and methods: This was an observational study. From each patient the following data were retrospective collected between January 2008 and September 2009: age, sex, DM in the family, smoking, HbA1c, hypertension (HTA) and dyslipidemia, microangiopathy and macroangiopathy, lipids and medical tr...

Introduction: Familial hypocalciuric hypercalcemia (FHH) has been classically characterized as an asymptomatic disease with mild hypercalcemia, hypocalciuria and inappropriately normal or high serum PTH concentration. The aim of our study is to assess the utility of genetic testing in patients with suspected FHH with atypical clinical manifestations, and the validity of classical biochemical parameters for the diagnosis.Description of methods: A retrospe...

Objectives: Verify the efficacy of the GLP-1 analogue exenatide in patients with type 2 DM assisted in our hospital area.Material and methods: This study included patients who initiated this therapy in 2008 and 2009. Through 3 months were analyzed the outcomes of weight, HbA1c and the development of adverse effects.Results: The process included 32 patients, 21 men and 11 women, with ages between 26 and 73 years old (mean age 48.78 ...

Introduction and objectives: In the 4th Workshop on Primary Hyperparathyroidism, it is recommended to perform BMD by DXA of third radius as well as lumbar spine and hip DXA in the initial assessment and follow up of patients with primary hyperparathyroidism. This test is not available in many centers, which means that only T Score values of the lumbar spine and hip are used to certify the absence of osteoporosis in asymptomatic patients wich conservative management is...

Glycosylated haemoglobin (HbA1c) is considered the Gold Standard parameter for evaluating long-term glycemic control in individuals with Diabetes Mellitus (DM). The presence of hemoglobin variants or others conditions that modify its glycosylation, can affect the veracity of its measurement. The detection of these hemoglobinopathies and his knowledge by the clinicians is very important for the correct diagnosis and follow-up. We present the case of a patient who presented a he...

Introduction: Assessing the effect of GLP 1 receptor agonist on metabolic control and weight loss in obesity and type 2 diabetes patients.Description of methods: A retrospective descriptive study involving type 2 diabetes patients and BMI >30 kg/m2, who started treatment with GLP-1-RAs during the years 2012–2014. Variables analyzed: weight and HbA1c at the begging, 6 months, 1 and 2 years; regimen at baseline and after GLP-1-RAs; inci...

Introduction: Myxoid tumors of the adrenal glands constitute an unusual entity and should be part of the differential diagnosis of atypical adenomas in the study of adrenal incidentaloma.Description of methods: We report the finding of myxoid adrenal adenoma in left adrenal gland in a 38-year-old woman.Case: PMH: Active smoker. Non hypertension, type 2 diabetes or dyslipidemia. No constitutional symptoms.Phys...

Introduction: Primary hyperparathyroidism is caused by a single adenoma in 85% of cases. This is why bilateral neck exploration seems to be a very aggressive procedure in a large number of cases. Intraoperative parathyroid hormone (IOPTH) monitoring could be a useful tool in primary hyperparathyroidism surgery allowing a less invasive surgical approach. The aim of our study is to evaluate the possible impact of the measurement of IOPTH during surgery.Met...